It is very common in southeast asia but has started to spread to europe and north america. A new intraoral appliance for trismus in oral submucous fibrosis. Osf can lead to squamous cell carcinoma, a risk that is further increased by concomitant tobacco consumption. This study was designed to determine the effect of pentoxifylline trental on the. Jun 26, 2010 the drugs used to treat oral submucous fibrosis osf were categorised into steroids, enzymes, cardiovascular drugs, antioxidants, vitamins and microelements. The surgical management of this condition involves excision of the fibrotic bands and interpositional grafts to retain the increased oral opening. Patients are advised to do mouthopening exercises, for example, by placing ice. It is a chronic insidious scarring disease of oral cavity, pharynx and. The habit is prevalent in south asian populations but has been recognized nowadays also in europe and north america. Oral submucous fibrosis and its various treatment modalities inclusive of both nonsurgical and surgical management.
Oral submucous fibrosis osf is a collagen disorder commonly seen in the indian subcontinent. Download surgery of trismus in oral submucous fibrosis. Oral submucous fibrosis osmf is a chronic, potentially malignant condition of the oral mucosa and the habitual. Pentoxifylline, a methylxanthine derivative, has vasodilating properties and is believed to increase the vascularity of the mucosal layer. Oral submucous fibrosis is a chronic, complex, premalignant 1% transformation risk condition of the oral cavity, characterized by juxtaepithelial inflammatory reaction and progressive fibrosis of the submucosal tissues the lamina propria and deeper connective tissues. Nov 24, 2012 oral submucous fibrosis osf is an extremely discomforting oral condition that is marked by the development of painful lesions inside the mouth that refuse to go away on their own. Colchicine is an ancient drug with antifibrotic and antiinflammatory properties. The available epidemiological data showed a clearcut geographical and ethnic predisposition, which suggested that certain. The present paper discusses in detail the effects of the components of areca nut on pathogenesis of oral submucous fibrosis. These are injected into the fibrotic bands weekly for 68 weeks with regular monitoring of mouth opening. Oral submucous fibrosis osmf is a potentially malignant disorder pmd and crippling condition of oral mucosa. Jan 30, 2017 oraoral submucous fibrosis osmf is a chronic, insidious, disabling disease of oral mucosa, oropharynx, and rarely, the larynx affecting millions of people worldwide with a prevalence rate of 0. Oral submucous fibrosis osmf is a chronic disease of oral mucosa characterized by inflammation and progressive fibrosis followed by stiffening of an otherwise yielding mucosa resulting in difficulty in opening the. Dec 25, 2014 oral submucous fibrosis osmf is a potentially malignant disorder of the oral cavity.
Apr, 2015 oral submucous fibrosis osf is a premalignant condition caused by betel chewing. Effectiveness of pentoxifylline in the treatment of oral. Oral submucous fibrosis in a 11yearold bangladeshi girl. The drugs used to treat oral submucous fibrosis osf were categorised into steroids, enzymes, cardiovascular drugs, antioxidants, vitamins and. Pindborg in 1966 as an insidious, chronic disease that affects any part of the oral cavity and sometimes the pharynx. It is a precancerous disorder and transforms into a malignant tumor in 1. Oral submucous fibrosis osmf, a precancerous condition of the oral cavity, has been studied by a number of workers in the field. Oral submucous fibrosis osf is a premalignant disorder associated with the chewing of areca nut betel nut. Histopathologic features of oral submucous fibrosis. Jun 18, 2018 oral submucous fibrosis is a chronic debilitating disease of the oral cavity characterized by inflammation and progressive fibrosis of the submucosal tissues lamina propria and deeper connective tissues. Oral submucous fibrosis causes, symptoms, treatment and. Download pdf surgery of trismus in oral submucous fibrosis. Yousuf a lakdawala, rida arshad and syeda maria fakhar abstract oral submucous fibrosis osmf is a debilitating precancerous condition of oral mucosa characterized by the fibrosis of oral mucosa, burning sensation in mouth, intolerance to spicy food and progression of the disease leading to limitation of mouth opening.
Intraoral appliance therapy can be employed as an alternative or adjuvant treatment for radiotherapyinduced fibrosis and autoimmune disorders such as scleroderma, psychogenic trismus, and oral submucous fibrosis, decreasing the adverse effects associated with other pharmacological interventions. Drug treatment for oral submucous fibrosis evidencebased dentistry. Osmf is characterized by deposition of dense collagen. Oral submucous fibrosis osmf is a potentially malignant disorder which was described by schwartz in 1952 as atropica idiopathica mucosae oris and later by jens j. Know all about the disease, including its possible causes, symptoms, diagnosis and treatment options. Oral submucous fibrosis a disease with malignant potential report. All such properties of aloe vera suggest the possibility of its use in the management of oral submucous fibrosis. Dr saikat saha mds, omfs, siliguri, west bengal, india. Oral submucous fibrosis osmf is a chronic, progressive, scarring disease, that predominantly affects people of south asia and southeast asia, where chewing of. The disease is rare in north america, and most cases seen in. A chronic deliberating disease of oral cavity article pdf available in iranian journal of pathology 64 january 2011.
Pdf classification system for oral submucous fibrosis. We planned to study the effects of colchicine in the management of oral submucous fibrosis. Oral submucous fibrosis results in marked rigidity and an eventual inability to open the mouth. Oral submucous fibrosis osf is an extremely discomforting oral condition that is marked by the development of painful lesions inside the mouth that refuse to go away on their own. Oral submucous fibrosis is a high risk precancerous lesion which predominantly affects indians, indians in diasporas, to a lesser extent in other asiatic, and sporadically in europeans. Evaluation of efficacy of aloe vera in the treatment of oral. All of these greatly interfere with patient quality of life. Please stop the habit of gutkha or betel nut chewing if you have. Oral submucous fibrosis osf, first described in the early 1950s, is a potentially malignant disease predominantly seen in people of asian decent. Jul 01, 20 oral submucous fibrosis osmf is a chronic, progressive disease that alters the fibroelasticity of the oral submucosa, prevalent in india and southeast asia but rare elsewhere, and characterized by burning and pain in the oral cavity, loss of gustatory sensation, the presence of blanched fibrous bands and stiffening of the oral mucosa and oro. Dr saikat saha mds, omfs, siliguri slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Compared to traditional betel quid, gutkha chewing tends to begin at a younger age and has a shorter time to the development of disease, so cases of oral submucous fibrosis have been seen as young as 11 years of age.
Oral submucous fibrosis 31 in europe or north america. The oral mucosa appears pale and atrophic figure 627. Existing treatments give only temporary symptomatic relief. Joshi subsequently coined the termed oral submucous fibrosis osf for the condition in 1953. Symptoms include submucous fibrosis, ulceration, xerostomia, a burning sensation, and restricted mouth opening.
Oral submucous fibrosis osf is a premalignant condition caused by betel chewing. Download fulltext pdf download fulltext pdf oral submucous fibrosis. Nov 14, 2015 one such reaction of the collagen of oral mucosa to arecanut is oral submucous fibrosis. Jun 17, 2016 oral submucous fibrosis is a chronic disease, treatment of which has largely been symptomatic. Oral submucous fibrosis osf is a high risk precancerous condition characterized by. Drug treatment for oral submucous fibrosis evidencebased. Trismus because of oral submucous fibrosis is a specific condition involving the mouth. A case of oral submucous fibrosis occurring in a 11yearold bangladeshi girl is presented. Oral submucous fibrosis osf is a precancerous condition of the oral mucosa. Oral submucous fibrosis can be seen at any age except for young children. Jun 01, 2017 oral submucous fibrosis and its various treatment modalities inclusive of both nonsurgical and surgical management. Betel nut and pan are freely available in the united kingdom, and in a city such as leicester, one might expect to find 3000 cases of oral submucosal fibrosis. Oral submucous fibrosis medical specialties clinical.
Oral submucous fibrosis, a clinically benign but potentially. Oral submucous fibrosis medical specialties clinical medicine. Proposed clinical classification for oral submucous fibrosis. Oral submucous fibrosis an overview sciencedirect topics. Spicy, pungent foods and irritants such as supari areca nut, paan betel lea. Oral submucous fibrosis free download as powerpoint presentation. Drug treatment for oral submucous fibrosis evidence. Oral submucous fibrosis osmf is a chronic disorder seen only in persons who chew betel areca catechu nuts, pan masala or gutkha and is characterized by tightening of the buccal, and sometimes palatal and lingual mucosae, causing trismus. Oral submucous fibrosis sf which is a relatively unknown disease in the early 60s is now widely regarded as a precancerous condition. The treatment of patients with oral submucous fibrosis depends on the degree of.
Oral submucous fibrosis osmf is a chronic disease of insidious onset and a prevailing potentially malignant disorder characterized by juxtaepithelial inflammatory reaction along with mucosal fibrosis. Jun 18, 2018 in 1952, schwartz coined the term atrophica idiopathica mucosa oris to describe an oral fibrosing disease he discovered in 5 indian women from kenya. Pdf oral submucous fibrosis osf is a premalignant condition caused by betel chewing. Management of oral submucous fibrosis by two different drug. Oral submucous fibrosisa case report medcrave online.
It is a chronic progressive disorder and its clinical presentation depends on the stage of the disease at detection. This study was carried out principally to confirm the diagnosis of oral submucous fibrosis, to provide a more detailed description of the histopathological changes occurring in osmf and to look for and record any new finding which might be detected. Over the last 40 years, many theories linking oral submucous fibrosis osmf to various risk factors have been proposed. Oral submucous fibrosis osf is characterized by abnormal collagen deposition. Oral submucous fibrosis osmf is a potentially malignant disorder largely seen in the southasian countries where areca nut is found to be the main predisposing factor.
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